While fragment based screening accepts relatively small screening deck of up to several thousand fragments to cover large chemical space, HTS typically requires much larger compound collection to succeed.
The initial steps of most modern drug discovery projects include high-throughput (HTS) or fragment screening. Personalized customer support and technical support via and via help button in the right corner of the bottom of your screen.Advanced filtering and sorting options, refine search results by structure option.properties, handling and transportation hazards etc. Additional information about compounds, e.g.Instant price and availability quotes with online ordering option.The database is constantly growing to cover novel developments and niche products. Chemspace database comprises over 240 million chemical building blocks including widely utilized primary and secondary amines, carboxylic acids, amino acid derivatives, alkylating and arylating agents, sulfonyl halides, aldehydes and ketones, alkylhydrazines and arylhydrazines, alcohols, phenols, thiols, amidoximes and amidines, aryl bromides and aryl iodides, boronic acids, organic azides, terminal acetylenes, fluorinated and spirocyclic compounds and many more. With the aim of addressing this demand, Chemspace focuses on molecules with less than 19 heavy atoms making its database attractive for medicinal chemists and drug design specialists. Medicinal Chemistry and Pharmaceutical Research remain solely reliant on synthetic chemistry methodologies and therefore demand diverse chemical building blocks offer meeting strict requirements in terms of not only physico-chemical properties but also chemical reactiveness. Diverse Chemical Building Blocks with Focus on Medicinal Chemistry With this approach, Chemspace makes it possible to cover the needs of various medicinal chemistry programs and pharmaceutical researches including lead oriented combinatorial synthesis, hit-to-lead and lead optimization projects, as well as the needs of synthetic chemistry providing reagents for click chemistry, couplings, and photoredox transformations. The products in our database range from widely demanded classes of chemical building blocks like amines and carboxylic acids to exclusively rare compounds like sulfoximines and phenyl bioisosteres. With more than 582 million chemical building blocks from numerous suppliers, Chemspace offers the most comprehensive coverage of the chemical space available through a single source.Įquipped with powerful database functionality and various search options including Exact Match, Substructure, and Similarity, Chemspace provides researchers with an ultimate tool for decision making and chemicals procurement. Therefore, we have gathered the largest database of chemical building blocks so that you can conveniently search tens of millions of compounds within a few seconds and enjoy the best purchasing experience. The Comprehensive Collection of Chemical Building BlocksĪt Chemspace, we aim to deliver chemical building blocks to fulfill the needs of your projects.
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